Endocrine Abstracts

Background: Isolated pituitary stalk (PS) lesions/thickening detected on imaging pose challenging dilemmas.Aim: Audit the diagnostic approach and management of patients with isolated PS lesions/thickening reported on MRI in a tertiary hospital.Methods: Reports of pituitary/brain MRIs performed in our Radiology Department between 1/2013 and 12/2015 were searched for the terms ‘stalk’, ‘infundibular’, ‘infund...

Introduction: Cabergoline is one of the medical treatments in acromegaly; it can be used alone or in combination with other available agents.Aim: To review the efficacy of cabergoline in patients with acromegaly treated in our centre.Patients and methods: Patients with acromegaly on cabergoline were identified from our Pituitary Registry. Clinical/laboratory/imaging data were collected and analysed.Results: F...

Introduction: Silent somatotroph Pituitary Neuroendocrine Tumours (PitNETs) are extremely rare (2−3% of surgically treated pituitary tumours) and data on their natural history and outcomes are scarce.Aim: To review systematically the cases of these tumours presenting in our Centre.Patients and methods: Patients with this diagnosis were identified from our Pituitary Registry and clinical/laboratory/imaging data were collected ...

Introduction: Functioning gonadotroph adenomas (FGAs) are very rare tumours secreting biologically active gonadotropins. In males, typically, FSH levels are elevated, whereas LH and testosterone are variable. Herein, we present three males with elevated, normal or low testosterone at diagnosis.Cases: Case 1:42-year-old man with two-year history of visual impairment. Bitemporal hemianopia was confirmed. Imaging showed macroadenoma compressing optic chiasm...

Introduction: Despite the significant risk of regrowth of non-functioning pituitary adenomas (NFAs) after primary treatment, systematic data on the probability of further tumour progression and the effectiveness of management approaches are lacking.Aims: Assess the probability of further regrowth(s), predictive factors and outcomes of management approaches in patients with NFA diagnosed with adenoma regrowth after primary treatment (surgery combined or n...